Tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells causing extrusion Of comedos. It also reduces hyperkeratinization that leads to microcomedo formation which is the initial lesion in acne. In dermis blood vessels vasodilation and angiogenesis and increased papillary demal collagen synthesis lead to lessening of fine and course wrinkling smoother texture decrease in hyperpigmentation.
Acnesol is used for the freatrnent ofthe following:
Acne
Pimples
Photodamaged skin
Hyperpigmentation
ADVERSE EFFECTS:
Tretinoin is a skin irritant and may cause peeling similar to that of sunburn. Sensitive individuals may experience oedema, buscemia and crusting of the skin
DIRECTIONS:
Apply gently on the affected areas 1-2 times a day or as directed by a physician.
CONTRAINDICATIONS:
Tretinoin is teratogenic and is contraindicated in pregnancy, breastfeeding mothers, on eczematous sunburn or branded skin.
Do not apply it with other topical treatment e.g. skin moisturizers,
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